Tag Archives: Brain Health

Vitamin D-Comprehensive

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It is only within the last few years that the important role Vitamin D plays has been researched and recognized.

Here are some facts regarding “Vitamin D” which is actually a hormone as opposed to a vitamin.
* Vitamin D, also called Calciferol, is a fat-soluble vitamin which means it is found primarily in animal fat. Unlike other vitamins that must be obtained solely through supplements or diet, vitamin D is manufactured in the body when sunlight comes in contact with the skin.

Here is a short list of what Vitamin D is responsible for.

  • Vitamin D is responsible for regulating over 800+ genes in the body!
  • It is a known fact that Vitamin D 25- Hydroxy levels lower than 15  will lead to many varieties of Cancer especially Colon Cancer
  • Vitamin D deficiency was responsible for older patients losing their balance and falling.  Two studies, one from the Journal of the American Geriatrics Society and the other in Pharmaco Economics support this theory
  • .Low Vitamin D associated with age related cognitive decline, dementia and Alzheimers.    In a new study published earlier this month in JAMA Neurology, researchers demonstrated a significant association between vitamin D insufficiency and cognitive decline that is specifically seen in Alzheimer’s disease and dementia. The results reinforce the importance of identifying vitamin D insufficiency among the elderly. Here, low vitamin D levels were associated with significantly faster rates of decline in memory and executive function performance..
  • Vitamin D has historically been used to treat Low Blood Pressure as there appears to be a correlation between blood pressure and low blood calcium levels and Vitamin D is directly responsible for where calcium should be and should not be.
  • Vitamin D is vital for bone growth and repair, especially in children and the elderly. Calcium and phosphorous levels in the blood stream are maintained by vitamin D. Vitamin D assists in the absorption of these important nutrients during digestion. This role in calcium and phosphorous absorption makes vitamin D an important part of bone growth and maintenance; and liver and kidney health Vitamin D also contributes to the function on the thyroid gland and to the immune system.

*The vast majority of the vitamin D used in the human body is manufactured in the skin. When vitamin D is consumed it is absorbed into the blood stream from the intestines with the help of bile. From the intestines Vitamin D is transported to the liver where it may be stored or used by the body. The daily Recommended Dietary Allowance (RDA) of vitamin D is 400 IU’s for an average adult man/woman.

Why suddenly is everyone Vitamin D deficient?

  • Not eating the foods high in Vitamin D which include fish liver oil, egg yolks, butter and cod liver oil. Vitamin D which naturally exists in milk is destroyed during the pasteurization process making it necessary to replace the naturally occurring Vitamin D that once was in the milk with synthetic Vitamin D which the body cannot utilize
  • Not enough sun exposure due to fear that the sun causes cancer when in fact that is not the case. Poor diet is!
  • Actually,  it may not be a deficiency of Vitamin D atoll, but a deficiency of Vitamin F, Vitamin D’s antagonist. Vitamin D picks up calcium from the gut and puts it into the blood. Vitamin F takes it from the blood and puts it into the tissues.

How to Optimize Vitamin D?

  • To optimize your levels, you need to expose large portions of your skin, such as your back, chest, legs, and arms, to sensible sun exposure. And, contrary to popular belief, the best time to be in the sun for vitamin D production is actually as near to solar noon as possible.
  • During this time you need the shortest exposure time to produce vitamin D because UVB rays are most intense at this time. Plus, when the sun goes down toward the horizon, the UVB is filtered out much more than the dangerous UVA.
  • Just be cautious about the length of your exposure. You only need enough exposure to have your skin turn the lightest shade of pink. Once you reach this point your body will not make any additional vitamin D due to its self-regulating mechanism. Any additional exposure will only cause harm and damage to your skin.

Vitamin D is important, but as we know, it is not the only key player. It is also important to assess calcium, magnesium, vitamin K2, and other trace minerals for deficiencies and support accordingly. There are several labs that can assess RBC minerals and fat-soluble vitamins.

What about Vitamin F–I never heard of this vitamin before?

  • Vitamin F is a source of essential polyunsaturated fatty acids which are needed to transport calcium from the blood to the tissues.
  • It contains Linolenic and Linoleic Acids which the liver will convert to Arachidonic Acid.  Arachidonic acid is the only form of polyunsaturated fat that can be utilized by the body.
  • It does not exist in vegetable oil—only in fat meat and butter—not margarine.
  • Because polyunsaturated fats reduce blood-cholesterol levels, they are much preferred over saturated fats.

D without F will cause the blood calcium level to increase at the expense of the tissue calcium level because Vitamin D not only picks up calcium from the gut in a deficiency of F, it brings calcium from the tissues back into the bloodstream and then targets the additional D to be stored by the Liver.

Vitamin F Deficiency results in or plays a major role in the following conditions::
* Hives                                     *Dry Skin
* Itchy Skin                              *Muscle Cramps (Charley Horse)
* Canker Sores (Herpes)        *Sun Poisoning
* Hypothyroidism                     *Sun Sensitivity
* Ridged Nails                          *Heat Prostration
* Poor Hair Quality                   *Prostate Problems

In my practice, I often recommend a blood test called Vitamin D 25-Hydroxy to determine the blood levels of Vitamin D.. Once the blood Vitamin D levels are determined, I may recommend specific supplements;hopefully on a short rather than long term basis.  I do not want my patients to stay on supplements forever, and prefer they increase their D levels using foods and the sun.

Note: Because vitamin D is stored in the body (in the liver), it can be toxic if taken in excess quantities. Vitamin D doses of three of four times the RDA may result in nausea, excessive thirst, confusion, heart rhythm abnormalities, weakness and headaches. Vitamin D is also known to interfere with certain medications including steroids and some seizure drugs. Point being do not take Vitamin D because it is a new fad–see a health care provider that knows what they’re doing, get the lab test and correct appropriately

There is a lot of chatter going on regarding Vitamin D.  For further information on the subject, feel free to contact me at [email protected] or 619-231-1778

Vitamin E & the Brain

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Vitamin E & the Brain

Among fat-soluble vitamins, vitamin E often gets sidelined in favor of compounds with better-known functions. People automatically associate vitamin A with vision and eye health, vitamin D with calcium homeostasis and bone health, and vitamin K with proper blood clotting. When vitamin E makes a rare appearance in discussions about health and nutrition, it’s often in the context of infertility, since deficiency of this nutrient is associated with reproductive difficulties  in animals and humans. But with advances in technology, scientists continue to uncover previously unknown and under-appreciated roles for vitamins and minerals. In the case of vitamin E, this nutrient might have a significant role to play in brain health and neurological function.

Results of a recent animal study support a requirement for sufficient vitamin E in order to deliver and maintain adequate levels of DHA and DHA-dependent phospholipids in the brain. Neuronal cell membranes are rich in cholesterol and polyunsaturated fats, which are highly susceptible to oxidation. With vitamin E having an antioxidant function, a deficiency can have dangerous consequences for brain health. In fact, severe vitamin E deficiency can manifest as cerebellar ataxia, demonstrating the importance of this nutrient for proper functioning of the central nervous system. Vitamin E deficiency also results in reduced myelination of spinal cord fibers, and leads to neuropathic and myopathic lesions all of which may have disastrous consequences for cognition and neuromuscular coordination.

A small, double-blind, placebo-controlled crossover study demonstrated that vitamin E supplementation led to improved scores on the Abnormal Involuntary Movement Scale (AIMS) in tardive dyskinesia patients who had had the condition for less than five years. The vitamin intervention was less effective in subjects with more longstanding disease.

The cerebrospinal fluid (CSF) of Alzheimer’s disease patients has been shown to be low in Vitamin E.While this specific finding may play a direct role in disease pathology, it might also simply be a reflection of overall poor nutrient status resulting, in part, from the modern diet, which is high in refined carbohydrates and low in micronutrients. However, considering the important role of vitamin E in the central nervous system, a lower level of this nutrient in CSF may expose neurons to profound free radical damage, leading to memory loss and declining cognitive function. Compared to placebo, patients with moderately advanced Alzheimer’s given 2000 IU of vitamin E per day experienced delayed deterioration of cognitive function. . Other studies indicate vitamin E is more effective in combination with another important antioxidant, vitamin C.

Reviews and meta-analyses of studies involving the use of supplemental vitamin E show mixed results, leading researchers to stress using caution regarding high doses of vitamin E. Some study authors suggest emphasizing food sources of vitamin E, or a multivitamin with around 30 IU of alpha-tocopherol, rather than isolated vitamin E supplements that deliver a higher dose. As is true for the use of any nutritional compound in a healthcare setting, caution should, of course, be practiced when dosing vitamin E. However, the mixed outcomes of studies employing vitamin E may be the result of confounding from the makeup of the supplements themselves. For example, a high alpha-tocopherol preparation may result in different effects than one with a higher fraction of gamma-tocopherol.

While frank vitamin E deficiency is rare, it is not unheard of. Vitamin E Deficiency can result from inborn errors of tocopherol transfer proteins, as well as disorders of lipid absorption, transport, and assimilation. Conditions that affect digestive efficiency, such as celiac disease and Crohn’s  disease, may interfere with proper absorption of fat-soluble nutrients. Biliary insufficiency resulting from compromised liver or gallbladder function may also contribute. An additional cause of vitamin E deficiency (as well as deficiency of many other nutrients) is bariatric surgery. While this can be a lifesaving procedure for many people, altering the anatomy of the digestive tract can have severe consequences for nutrient absorption, and extra care should be given to ensuring sufficient nutrient uptake in the body.

The foods richest in vitamin E are nuts and seeds, whole grains, and vegetable oils, such as corn, soybean, and safflower oils. However, overly large intake of these oils is not recommended, due to the potential for skewing the dietary omega-6/omega-3 fatty acid ratio toward the generally pro-inflammatory omega-6 pathways.

NOTE: GCEL (Glutathione) is 5000 times stronger than Vitamins C & E,

  • Vitamin C has 5 extra electrons to donate
  • Vitamin E has 3 extra electrons to donate
  • GSH has 1 million extra electrons to donate