My Pathway to Healing

My Pathway to Healing

My practice is about healing the human mainframe using a variety of techniques learned over the years. One of my greatest gifts is to work with a patient on their level and gradually groom them to a position of “empowered self-healthcare” that is not only comfortable but also easy to maintain.

As a teenager, my interest in health began with food. I studied  raw foods at the Hippocrates Institute in Boston, then moving onto Macrobiotic studies also in Boston and New York.  I was then and still am a believer in “Let food be thy medicine and medicine be thy food”

While attending Chiropractic school in  Georgia, I was a founding member of Life Grocery Co-Op in Marietta then moving onto being a silent partner in one of the first health food stores in Atlanta. I  resigned because one partner wanted to sell vitamins & I wanted to promote food not supplements.

What led me to Chiropractic was the actual ART of the profession. Adjusting the spine which is a continuation of the brain creates a change in the patients unique vibrational tone always for the better.  The higher the vibration or resonance the less likely it is to attract sickness and disease.  Does the word Disease really mean Dis-Ease?

Chiropractic was never intended to “fix” sore backs. In the early days, patients went to see their Chiropractor when they felt better than ever and wanted to keep it that way—not because they had a backache.  The “old timey” Doctors of Chiropractic felt it was a failure on their part if a patient was sick as it meant they were not doing their job appropriately.

In the “early days” Chiropractors gave a weekly “lay lecture” educating  patients on diet and lifestyle often requiring mandatory attendance.  They knew education was essential as do I.

During school and with a little bit of  NASA insight,  I was exposed to the piezoelectric effect of crystals, angstrom frequencies hard drive, memory, color, sound, music, and a host of other factors that can affect vibrational tone. This was pioneering work for its time (1976).  I also studied the spiritual and mental aspects of healing and how they had an enormous  impact on well-being.  Hence the 12 Positive Volitions were born, and  the Secret to Healing is the Power of Belief became one of my theorems.

Without a doubt, food is indeed the best medicine, however, there are those who do require additional support by way of supplements and pharmaceuticals to put them on the correct path to health.  

This led me to become an astute and outstanding researcher into supplementation. I wanted to know everything about a product  from its’ origins to its bottling-thus enabling me to feel  comfortable recommending them to my patients.  In my practice, strategic supplementation is the name of the game. There are no two people alike and one supplement does not fit all. Supplements when needed, are just one of the many tools I use to get the job done.

In today’s healthcare market, it seems Functional Medicine is the new buzz word. I have been practicing Functional Medicine  43 years before there was terminology to describe what it is that I do. 

We are vibrational beings with a unique vibrational tone. In closing, my work is about providing a framework of  healing using  all available tools to expound and enhance the human  capability to heal with respect, dignity and grace.

Dr. Philip Peter Princetta

Juice Your Way to Health

After 43 years in practice, it is part of my intention to return to some of the basics I originally used at the beginning. This includes Bitters for digestion, the Alphabet of Vitamins ( A, B, C, D, E, F ); Cod Liver Oil; and JUICING

This post is about the latter and in it I will introduce the benefits in a nutshell as to why this should be part of your life

We will begin with a caveat or two:

  • Juicing is a concentrated form of eating. An example would be that it takes a number of carrots, apples, or whatever, to make a glass juice; and we normally would not eat that amount at a single seating.

So , I highly, highly, highly you get a good book that is easy to follow and your are comfortable with. You may have to try a few books before you find the book(s) that is right for you.

  • Until you get it down to an art and science, juicing can me be a bit on the messy side and time consuming. You not only have to prep the veggies by washing them , you have to clean the juicer when you are finished. But it is well worth it.

To get around this issue, I recommend

  • Investing in a good quality Juicer
  • Stage a “juicing area” in your kitchen or workspace if at all possible
  • Although forbidden by the strictest of juicing gurus, make extra juice ahead of time; store it in Ball jars; and in the fridge it goes. When I make Dr.P’s Magic Green Drink, I make 2-3 extra quarts to last 2-3 extra days.

Why Juice?

There are so many reasons for juicing. Here are just a few:

  • Supports the Liver is Your Lifeline
  • Restores a better health perspective especially if cancer or other serious diseases are present
  • Allows the entire digestive system to revamp itself by not having to constantly process food
  • Loaded with alkaline nutrients!
  • Totally unprocessed!
  • Absorbed immediately!
  • Contains loads of protein! Yes, protein!
  • Loaded with live food enzymes!
  • Provides energy!

I do believe that juicing should be a part of your life. Unless health issues warrant, I do not believe your diet should be only juice. Mix it up. Perhaps some days it’s only juice; while other days, juice just once a day; and yet other days no juice. You will know what is right for you because you will know how you feel

NOTE: Specific conditions have specific juices. An example of this would be cabbage juice for GERD and a host of other GI issues.

Here are my suggestions for two of the thousands of juicers out there

And as you may know or soon will find out, there are a million books on juicing. The one above works for most people but again as stated above, you may have to go through a few books before finding one that works for you. This one is a good overall publication

And as you may know or soon will find out, there are a million books on juicing. The one above works for most people but again as stated above, you may have to go through a few books before finding one that works for you. This one is a good overall publication

Vitamin-D and ImmuneFunction

Vitamin-D and Immune Function

By: Cat Ebeling, RN, MSN-PHN, co-author of the best-sellers:  The Fat Burning KitchenThe Top 101 Foods that Fight Aging & The Diabetes Fix

Vitamin D from the sun has existed for a long time as an immune booster. In the 1800’s when many people had tuberculosis, sunshine was known to have curative powers, and sick patients flocked to sanitariums in sunny places to soak up the healing sunshine. Cod liver oil, also a rich source of vitamin D, has also been around for decades as a preventative for infections, colds and flu.

Studies show that vitamin D regulates many functions in the body, including hormone balance, metabolism, blood pressure, bone density, fighting cancer, and immune function (ever notice that people tend to get colds and flu in the winter when the sun is low?).

Vitamin D is critical for our health. We know that vitamin D is essential for healing and protecting against many contagious diseases and chronic diseases. Low levels of vitamin D are associated with upper and lower respiratory infections, heart disease, asthma, cancers, diabetes, multiple sclerosis, HIV, hypertension, inflammatory bowel disease, Alzheimer’s disease and other autoimmune diseases. Vitamin D deficiency is a worldwide public health problem in both developed and developing countries.

Did you know that our bodies contain cell receptors for vitamin D in virtually every system of the body? That tells us that vitamin D is necessary for virtually all body functions. Vitamin D actually influences the expression of over 200 health-supporting genes in our bodies.

There’s a lot of buzz about vitamin D boosting immune function to fight off colds, seasonal influenza, and other viruses. Research suggests that vitamin-D deficiency may one of the primary reasons people get more colds and flu in the winter when sunshine is less available.

As many as 70 percent of Americans are considered deficient in vitamin D. The elderly, females more than males, those who live the far north or south of the equator, people with darker skin pigmentation, those who work and stay inside during the day, and people with poor dietary habits generally have the lowest levels of vitamin D.

How does vitamin D boost immune function?

The immune system is an incredibly complex protective mechanism, but to simplify, we can divide the immune system into two main categories: innate immunity, and adaptive immunity.

Innate immunity is our nonspecific defense mechanism that activates in the presence of an invading pathogen. So, even if you have never been exposed to a virus or pathogen, your body has a built-in ability to protect itself from an invader. This part of your immune system is your first line of defense against any type of new type of germs—whether it is bacteria, viruses, and fungi. And it’s super important to be sure this line of defense is strong.

The other type of immune response is your adaptive immune response. This immune response is active against pathogens that you have previously encountered. The body recognizes, adapts and attacks specific invaders much more efficiently.

In the case of brand new types of influenza strains, the body has not had a chance to develop specific antibodies against it yet. So, this is where we call in the powers of our innate immune system to protect us. Vitamin D works to strengthen this innate immune system response.

Many different studies have associated vitamin D with its power to fight infection. One report looked at almost 19,000 people and found that the individuals with the lower levels of vitamin D were more likely to report upper respiratory tract infections, than those with sufficient levels of vitamin D.

This study looked at 800 people in Finland, and found that those with the lowest levels of vitamin D lost more days at work due to respiratory infections. Other studies have focused on how vitamin D helps to prevent influenza, colds and even HIV. And this well-designed study using therapeutic doses of vitamin D showed that vitamin D administration resulted in a statistically significant (42%) decrease in the incidence of influenza infection.

Vitamin D works by boosting the strength of the immune system while lowering inflammatory reactions. This makes vitamin D a powerful immune modulator. It helps boost immune power, but prevents the immune system from overreacting, as in the case of autoimmune disease.

How does it work? Vitamin D strengthens particular cells within the immune system, such as the T cells. It also helps to decrease levels of inflammatory cytokines, a part of the immune system that can overreact with dangerous outcomes.

There are three ways to get vitamin D levels up in your system. One—you can take a vitamin D3 supplement. D3 or cholecalciferol is most easily utilized in the body, over vitamin D2. Secondly, you can get some vitamin D from foods and third, you can get vitamin D from the sun—IF you are in an area where the sun is strong enough. Depending on the latitude where you live and the time of year, you may or may not be able to get vitamin D from the sun. In my opinion, however getting vitamin D from sunshine is the best way if you can.

The sun’s rays are too weak in the winter generally (depending on the latitude that you live). Even if you can get outside in the winter, if you live north of say, Los Angeles to the west and Atlanta Georgia to the east, you won’t be able to get enough sun from November through February.

The only way for our bodies to make vitamin D from the sun is to allow the UVB rays of the sun to reach our skin. That means we need to expose enough skin for 20-40 minutes without sunscreen at the strongest times of the day, between the hours of 10am and 2pm.

UVB rays are the rays that cause sunburn, just don’t overdo it! Full-body exposure of pale skin to summer sunshine for 30 minutes without clothing or sunscreen can result in the synthesis of between 10,000 and 20,000 IU of vitamin D.

However—if you don’t supplement with vitamin D3 in the winter you’re can pretty much count on being deficient in vitamin D in the winter.

Supplementing with vitamin D has a wide range of ‘suggested’ dosages, and you can overdo it with this fat soluble vitamin and create adverse health effects. While some doctors advise people to take 5000 to 10,000 Iu per day of vitamin D, this can be too much and a safer range would be around 5,000IU vitamin D3 per day.

Studies show the fat-soluble vitamins A, D, and K work synergistically, so adding adequate vitamin A and K2 may protect against toxic effects of excess vitamin D. Sufficient levels of potassium and magnesium have also been suggested to protect against vitamin D toxicity.

Lastly, be sure to get plenty of healthy food with natural sources of vitamin D, such as egg yolks, wild caught salmon and mackerel, organ meats, and some mushrooms. And avoid those processed foods with added vitamin D—those do nothing for your health.

Some of the best absorbed vitamin D comes from taking some cod liver oil daily. Make sure to take only small doses of cod liver oil (enough for 50% to 100% DV of vitamin D), as large doses can give you an overdose of Vitamin A.

One more thing to point out as we near the end of winter, sunlight has far more beneficial benefits for our health than just increasing our vitamin D.

A recent 20-year study following 29,518 subjects found that those individuals avoiding sun exposure were twice as likely to die from all causes. Sunlight helps us make more endorphins, the natural chemical in our bodies that makes us feel relaxed and happy.

Sunlight promotes production of a peptide that helps to dilate the blood vessels, lowering blood pressure, and it helps create another substance called ‘Substance P’, that promotes better blood flow and regulates the immune system in response to acute stressors. And one more benefit of sunshine, it helps to reduce appetite, increase the libido and gives you a nice looking golden glow, while regulating your sleeping/waking cycle better.

If you want to stay healthy and strong, it’s not only wise, but essential to spend time outdoors in the sunshine. Soak it up!

References
https://www.nytimes.com/2020/03/10/well/live/can-i-boost-my-immune-system.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/
https://chriskresser.com/vitamin-d-more-is-not-better/
https://www.sciencedaily.com/releases/2019/04/190417111440.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821804/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/#B7-nutrients-05-02502
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/

Dr. P’s COVID Protocol Impressions

Dr. P’s COVID Impressions

Although we now have parts of and in some cases all of some form of vaccine, I am asking my patients and all others who may read this put to Not Let Their Guard  Down!  Due Diligence is imperative in times such as these and when dealing with a virus that has the propensity to create many variants

With so much information regarding protocols for COVID, I though I would at least put all my emails along with various articles which I felt had merit and worth into one post on my website. All articles/links a have indeed been Fact Checked.

Let me make it crystal clear that One Size Does Not Fit All !

So here goes my take

Dr. P’s Humidifier Technique                                                

  • Cool Mist Humidifier (Walmart $50-)                                  
  • 1 Gallon Distilled Water (Must be Distilled)                        
  • 1 Quart Hydrogen Peroxide                                                   
  • 18-20 Drops Oregano Oil                                                        
  • 1 Tablespoon of Silver 500   

NOTE:  I recommend always to have the following on hand just in case as this is my go to for many conditions but especially pneumonia

  • A Nebulizer
  • Mild Silver Protein
  • DMSO or Albuterol

 Curing Viruses with Hydrogen Peroxide Can a simple therapy stop the pandemic? Commentary by Thomas E. Levy, MD, JD

Dr. David Brownstein Discusses Nebulized Peroxide

MASKS: I do believe in Masks. I recommend a light spray of Oregano Essential Oil or my very favorite Thieves on the actual Mask enabling me to inhale these excellent antimicrobial oils and further protect myself whenever I put the mask(s) on!

ApHinity Clean Air Products

Chlorine Dioxide has been used for years to kill airborne pathogens –this now includes the COVID 19. I use them at home, at my office and at the hotel in Atlanta.
This makes the Aphinity product  worth looking into.  You can call the office and ask questions but they will refer you to Steve who is an encyclopaedia how these work.

I do know that one packet is good for 5-600 sq. ft and may last up to two months–Check with Steve, he will provide good sound advise

Basic Immune Protocol

Beta 1,3 D Glucan 100/500

The most studied immune system modulator in the world.  Available in 100mg which I recommend for children; and 500mg for adults at a dosage of one capsule per day

You Tube Transfer Point Beta 1,3 D Glucan

https://www.youtube.com/watch?v=boZ1YiJGH6Y

Beta Glucan and Cancer Dr. Vaclav Vetvicka

Astaxanthin

6,000 times stronger than vitamin C (more electrons to donate)
• 800 times stronger than CoQ10 
• 550 times stronger than green tea catechins (strongest of all catechins)
• 75 times stronger than alpha lipoic acid 

19 Known Medical Benefits of Astaxanthin

Astaxanthin Helps Alleviate Corona Cytokine Storm

N-Acetyl Cysteine (NAC)

This Mercola / Dr. Seheult article/video on NAC is worth having a look at. Way before COVID 19, I have recommended NAC for many patients. I myself take one per day for lung/pulmonary support even though it does not appear that I have any issues there. NAC is also a precursor to Glutathione and Glutathione is the body’s “top cream of the crop” # 1 Antioxidant having a direct effect on everything in our bodies

NAC

Vitamin D (K2 D3 5000) or (Vitamin D3 Complete 5000)

At the forefront of the COVID pandemic from its very onset,  is Vitamin D and how its receptor sites are imperative in strengthening our immune system.  All Vitamin  D products are not the same so be careful to purchase only the best.  Remember Vitamin D without Vitamin K is useless

NOTE: I am a firm believer in a blood test to determine Vitamin D levels. A test such as this will determine the dosage. If your doctor will not order for you, contact me and I will send you a requisition for LabCorp.

Vitamin D and Immune Function

Gut Health Disease _ Vitamin D

Detoxified Iodine

Edgar Cayce’s Detoxified Iodine is just what it says it is which is Iodine that has been Detoxified

For this product, I recommend 6 drops in mouth; swish around; gargle and swallow.  Once or twice a day seems to work—just to keep the throat and tonsillar area free of bacteria and virus that should not be there

  • Zinc Glycinate (optional)
  • Liquid or Liposomal Vitamin C
  • Quercetin (Reg. / Phytosome) 

Zinc Glycinate or Picolinate

The trace mineral Zinc has become important in the fight against COVID-19. The reason why I am cautious with Zinc is that  it is possible to get too much zinc, which can actually depress your immune system and negatively affect your health. 

I therefore recommend using Zinc one or two weeks per month.

Standard Process Labs has had a test to determine if you need Zinc for well over 60 years

Vitamin C:

Enough cannot be said about Vitamin C when it comes to Immune System overall health.  Linus Pauling is the only person holding not one but two Nobel Peace Prizes for his work on the benefits of Vitamin C

I use  two different varieties of Vitamin C and as with Vitamin B,, I like my patients to use smaller  dosages through the day

  • Liposomal (from France)
  • Powder Vitamin C  (from Israel)

Quercetin:

Although a Flavonoid and an excellent one at that.  I do not use Quercetin in my COVID Protocol basically because  I feel it is not necessary and “enough is enough:

Additionally:

Nano Soma

NANO SOMA is made from all natural, food-based ingredients and has no known side effects. It is commonly called policosanol and is present in foods such as rice, sugar cane, wheat, and peanuts.

Nano Soma work specifically with the Vitamin D receptors in the body and also teaches the body how to make its own Vitamin C which humans were capable of doing at one time

www.thenanosoma.com.

https://www.researchgate.net/profile/Palayakotai_Raghavan.

https://www.researchsquare.com/article/rs-34021/v5

Nano Soma in vitro Inhibits SARS- COV-2

The following two items are pharmaceutical based and have held my interest since day one.  Both are anti-parasitic; both are used for Rheumatoid Arthritis and Lupus and both MAY have an enormously positive effects on COVID with minor side effects if any.

NOTE: Quinine is a Zinc Ionophore, British Soldiers stationed in India & Africa were told to take Quinine to prevent Malaria. However, Quinine is extremely bitter so they had to add fruited water and sugar to take it. Hence the expression “Just s little bit of sugar makes the medicine go down” Ultimately the British government gave permission to add 1 teaspoon of gin to the quinine and the Gin & Tonic was born. Tonic by the way is composed of Quinine, Fruited Water and Sugar!

I again end with the paragraph at the beginning which states

Although we now have parts of and in some cases all of some form of “vaccine”, I am asking my patients and all others who may read this put to Not Let Their Guard Down! Due Diligence is imperative in times such as these and when dealing with a virus that has the propensity to create many Variants

Should you want information on any of these recommendation or even better, a discussion about any of them, please email or call me at 619-231-1778

Dr. P’s Humidifier, Silver Nebulizer Technique

Dr. P’s Humidifier, Silver Nebulizer and Silver IV Protocols

  • Cool Mist Humidifier (Walmart $49.99)
  • 1 Gallon Distilled Water–MUST be Distilled
  • 1 Quart bottle of Hydrogen Peroxide18-20 drops Oregano Oil
  • 1 Tablespoon Silver 500
  • Add ingredients together and rest well 
  • Aside from the bedroom for sleeping, some folks set one up in the living room or any space they are hanging in.

Use when feeling stuffy; cold; flu; coughing; and anything respiratory including nCOVID-19

** All Oregano Oils are not the same nor the difference between Colloidal Silver and Silver Protein

NEBULIZER TECHNIQUE

  • Fill cup 1/2 to 3/4 full of silver 500
  • Add 2 drops of DMSO if available OR if by chance you happen to have Albuterol, call me to discuss how to use for this recipe
  • Do a breathing session

The best nebulizer for your money is made by InnoSpire Elegance Compressor Nebulizer System

Purchase from Just Nebulizers   1-888-550-2450 (M-F 8AM-6PM EST)

Ask about purchasing extra disposable and non-disposable mouthpieces.  Not a bad idea to have extra on hand –and not just because of nCOVID-19 but the many other respiratory issues out there.

NOTE: The Nebulizer Silver technique is my ACE in the HOLE when it comes to preventing treating pneumonia.

Erectile Dysfunction: The Canary in the Cardiovascular Coal Mine?

Erectile Dysfunction: The Canary in the Cardiovascular Coal Mine?

The role of endothelial function on tumescence – and beyond


By Erica Zelfand, ND

The stories I hear of men* with erectile dysfunction (ED) are strikingly similar: The issue begins insidiously and is initially treated at a “low T clinic” with gradually increasing doses of exogenous testosterone in regimens that yield varied but ultimately insufficient results.

A review of the lab work of these individuals reveals that they are typically overdosed on their prescription hormones, with total testosterone levels often above 1000 ng/dL. While supraphysiological levels of testosterone do, in fact, enhance the sexual desire and performance of some men, they come with significant health risks and pesky side effects like anxiety, irritability, and insomnia. Other men, however, find that even high doses of anabolic steroids fail to engender desired outcomes in the bedroom.

Erectile dysfunction (ED, impotence) is a fairly common medical condition, characterized by the inability to achieve and maintain a penile erection firm enough for satisfying sexual intercourse.1 ED is also on the rise: While the condition affected an estimated 152 million males worldwide in 1995, that number is expected to swell (no pun intended) to over 320 million people by 2025.2,3

Just last week, a new patient shouted at his wit’s end, “I’m taking testosterone, HCG [human chorionic gonadotropin], and anastrozole. I’m lifting more weight than the other guys at the gym. I look amazing. I have tons of energy—so much I can’t fall asleep at night – but I after two years of playing with all my doses I still can’t get hard. What the heck is wrong with me!? What are my other doctors missing? I really hope you can figure it out.” [Note: This patient employed more expletives when expressing himself.]

Time and time again, I explain to exasperated fellows like this one that sex hormone levels are just one piece of the puzzle. The successful treatment of ED often also entails assessing the nervous system (including mental health), adrenal function, metabolic health, and endothelial integrity, with the latter being among the most overlooked aspects of sexual health.

Tumescence is a hemodynamic process characterized by enhanced penile arterial inflow and reduced venous outflow.4,5 Because the physiology of tumescence (penile erection) requires that the penis engorges with blood, the integrity of the vascular system—and ergo the status of nitric oxide production—is of utmost importance to male sexual performance and satisfaction.6


Nitric Oxide: The Endothelium Relaxer

Our understanding of nitric oxide (NO) is relatively new: In 1998 three American pharmacologists received the Nobel Prize for their discovery of NO’s effects as a signaling molecule within the cardiovascular system.7

This tiny gas molecule is produced in the blood vessels, nerves, and immune cells. Neuronal and endothelial NO causes relaxation of the surrounding smooth muscle, resulting in vasodilation.8,9 With regard to male sexual health, NO triggers the relaxation of the cavernous smooth muscle of the penis, allowing for engorgement and  subsequent erection.

NO production declines with age, however, placing males at increased risk of ED as they grow older.10 It is now estimated that nearly half of men above the age of 40 have some degree of ED.11

Endothelial inflammation undermines NO production and is thus a significant determinant of ED and other vascular diseases.12 It is also a culprit that can effectively be treated with naturopathic medicine.


Erectile Dysfunction as Coronary Risk Marker

Due to the relatively small size of the penile vasculature (on even the most well-endowed of individuals), ED may be understood as a warning sign of poor vascular function and impending coronary artery disease (CAD).9,11,13,14 ED may present well before the observation of so much as an elevated blood pressure reading.15 If left unchecked, the vascular inflammation and dysfunction associated with many cases of ED may lead to ischemic heart disease;16 ED has thus been referred to as “penile angina.”17

ED is such a strong predictor of cardiovascular disease in men,3 in fact, that providers are now advised to assess the cardiovascular health of patients presenting with the condition.16 While not all men with ED have cardiovascular problems, a significant percentage of males with angiographically demonstrated CAD have been observed to have ED.13 ED was also shown in one study to precede CAD in a whopping 70% of male CAD patients.13

It is perhaps no surprise that ED and CAD go hand-in-hand, as they share many of the same risk factors, including sedentary lifestyle, obesity, diabetes, smoking, hypertension, dyslipidemia, metabolic syndrome, and declining NO activity.9,11,18,19

Conventional Treatments of ED

The first-line therapy for ED entails phosphodiesterase type 5 inhibitors (PDE5i) like sildenafil.20 Although these drugs do not directly increase NO, they do augment NO-mediated pathways.21

When PDE5i’s fail to improve symptoms, vacuum devices, intracavernous injections, and penile prosthesis implantation are considered second- and third-line therapies. Few patients are eager to try these interventions, however, which may not be too great of a tragedy, as none of these methods adequately addresses the underlying metabolic, neurological, hormonal, or endothelial aspects of ED.

Testosterone plays an important role in sexual function via several mechanisms, including the stimulation of NO release.22 As more and more males become afflicted with ED, the increasing number of “low T” clinics that have cropped up over the years now comprise a multi-billion-dollar industry.23,24 Testosterone replacement therapy (TRT) does help many men with ED—though not all. In my experience and opinion, focusing on NO augmentation—either in lieu of or in addition to hormone prescription—may serve ED patients in both the short and long term.

Erectile Dysfunction: The Canary in the Cardiovascular Coal Mine?

Two Pathways of Nitric Oxide Production

There are two pathways by which NO is created in the body (see Figure 1).25 One pathway entails the reduction of dietary nitrates to nitrite and then NO.26 Another pathway depends upon the enzyme nitric oxide synthase (NOS) to convert L-arginine to NO.27

Oral Hygiene

In the NOS independent pathway of NO production, facultative oral microflora reduce dietary nitrates (NO3) to nitrites (NO2), which are then converted to NO in the acidic environment of the stomach.26

In this pathway, the presence of particular oral bacteria and the stomach’s low pH are invaluable for NO production. These requisite conditions are undermined, however, by antiseptic mouthwashes, proton-pump inhibitors, and over-the-counter antacid medications—agents commonly used in industrialized societies.28–30 Although restoring a patient’s gastric acidity is a relatively straightforward task for the naturopathic physician, as of this writing there is no nutritional probiotic supplement that contains the oral bacteria essential for nitrate reduction. We may still, however, advise patients to avoid commercial mouthwash products.26


Dark Leafy Greens and Beetroot

Vegetable-rich diets have been shown to support heart health,31,32 in part due to their nitrite and nitrate content. High nitrate diets lower the risks of hypertension, heart attack, and stroke,33–35

Although dietary nitrites such as those naturally found in bacon have been vilified, nitrites and nitrates are actually naturally occurring molecules produced in the body that are important to health.36,37 (The culprit in processed meats is likely not nitrite, but rather the carcinogenic compound nitrosamine.38,39)

In addition to eating plenty of green, leafy vegetables, powdered greens products, beetroot (also known simply as “beets”), and beetroot products may all be used as supplemental sources of nitrates, antioxidants, and phenolic compounds pertinent to cardiovascular health.40 Beetroot is a particularly rich source of nitrates and antioxidant compounds and has been observed to increase NO levels and lower blood pressure readings in both men and women of various ages.41–43

Although dietary nitrites such as those naturally found in bacon have been vilified, nitrites and nitrates are actually naturally occurring molecules produced in the body that are important to health.36,37 (The culprit in processed meats is likely not nitrite, but rather the carcinogenic compound nitrosamine.38,39)

In addition to eating plenty of green, leafy vegetables, powdered greens products, beetroot (also known simply as “beets”), and beetroot products may all be used as supplemental sources of nitrates, antioxidants, and phenolic compounds pertinent to cardiovascular health.40 Beetroot is a particularly rich source of nitrates and antioxidant compounds and has been observed to increase NO levels and lower blood pressure readings in both men and women of various ages.41–43

L-Arginine and L-Citrulline

L-Arginine may be acquired from nutritional supplements and/or endogenously derived from the amino acid L-citrulline, and serves as the source raw material from which the body produces NO via NOS (Figure 1).44 Low serum levels of L-arginine have unsurprisingly been correlated with poor NO production.45

A significant percentage of ED patients have low L-arginine or L-citrulline levels, placing them at increased risk of disease.45 Because of this and because the NOS-dependent route of NO production was the first pathway discovered, the nutraceutical product market is now replete with L-arginine-containing formulae.46

Although oral L-arginine supplementation may improve NO-mediated vasodilation and endothelial function, its effects as a monotherapy are transient due to the short duration of its presence in the circulation (on the order of milliseconds).47 This may be why a review of L-arginines efficacy in the treatment of ED reports that a minimum dosage of 3 g daily is necessary to achieve outcomes. Some studies have even dosed the amino acid at 5 g and higher.48

The efficacy of L-arginine may be improved by delivering it alongside N-acetylcysteine or glutathione (GSH), both of which contain sulfur residues or thiols. NO binds GSH, forming S-nitrosoglutathione. This molecule then transports and circulates NO, has a half-life of hours, and is just as vasoactive as NO.49 Antioxidants like ascorbate also are able to cleave or release bound NO.50 L-arginine also pairs particularly well with Pycnogenol, as is explored in the section below.

Unlike L-arginine, its precursor L-citrulline (named for the watermelon, or Citrullus vulgaris, from which it is derived51) evades presystemic metabolism, effectively increasing circulating NO levels.45,52,53 This may make L-citrulline a more advantageous nutritional supplement than L-arginine in the treatment of ED, hypertension, and related vascular conditions.54,55

Although L-citrulline supplements are less effective than PDE5i’s (at least in the short term), they are an effective adjuvant to PDE5i treatment.54,56 L-citrulline has also been shown to be safe and psychologically well tolerated.54

What may be even more effective than L-arginine or L-citrulline monotherapy, however, is the administration of the two NOS substrates concurrently: Simultaneous oral supplementation of L-arginine and L-citrulline (1 gram of each) increased plasma L-arginine levels more than 2 g of either alone in a 2017 study.57 (Note that because many viruses, including herpes simplex virus [HSV], are dependent upon the bioavailability of arginine,58 L-arginine and L-citrulline supplements may be poorly tolerated by patients with frequent HSV outbreaks.)

In addition to augmenting the body’s supply of L-arginine, it is also important to support conversion of the amino acid into NO.38 This conversion is enhanced by oxygen, NADPH, heme, tetrahydrobiopterin (THB, also known as BH4), and other coenzymes. Things as simple as checking oxygen saturation and ferritin levels may therefore prove advantageous.


Pycnogenol

A standardized extract from the bark of the French maritime pine, Pinus pinaster—or Pycnogenol, as it’s known in the US by its patent name—can improve erectile function both as a stand-alone treatment and in combination with L-arginine.59,60

In a double-blind study of 21 males suffering from ED, patients received 120 mg of Pycnogenol or placebo daily. After three months, Pycnogenol significantly improved the symptoms of ED from moderate to mild stage. Perhaps more importantly, a significant increase in plasma antioxidant activity was noted among those who received Pycnogenol, while no such benefit was found in those who received placebo. The Pycnogenol group further enjoyed reductions in total cholesterol and LDL-cholesterol levels (from 5.41 to 4.98 mmol/L and from 3.44 to 2.78 mmol/L, respectively). (No significant changes in triglycerides or HDL were observed.) These findings suggest that Pycnogenol may not only treat ED but may also temper some of the more serious vascular changes that succeed it.61

In another study of 40 males, 25 to 45 years of age, a combination of L-arginine and Pycnogenol significantly outperformed Pycnogenol alone, helping 80% of men (and, after another month of the study, 92.5% of men) achieve a normal erection – as compared to only 5% of men who benefitted from Pycnogenol alone. Pycnogenol was given at a dose of 40 mg one to three times daily, with L-arginine at a dose of 1.7 g daily.60 (It is worth noting that the minimum effective daily dosage of L-arginine as a standalone treatment of ED may be 3 g,62 though this study suggests that lower doses may be used within the milieu of co-treatment with Pycnogeol.)

In a similar trial of 50 males, L-arginine (3 g/day) plus Pycnogenol (80 mg/day) restored normal erectile function after just one month of supplementation. Sperm quality improved in the men who took this combination and their testosterone levels increased significantly. The men also reported a doubling in their sexual intercourse frequency.63


Glutathione and Other Antioxidants

Supplementation with L-citrulline and GSH has also been shown to synergistically increase NO levels.

In addition to providing thiols for the formation of S-nitroso glutathione, GSH also affects the NOS enzyme function. In a GSH-depleted environment, NOS becomes uncoupled, resulting in the production of toxic superoxides instead of salubrious NO. Endothelial NOS (eNOS) uncoupling has been implicated in numerous conditions marked by vascular endothelial dysfunction, including heart failure, ischemia/reperfusion injury, hypertension, atherosclerosis, and diabetes.65

As the master antioxidant of the body, GSH strongly protects against the oxidative stress associated with endothelial dysfunction. Like other antioxidants, GSH may prevent eNOS uncoupling by scavenging free radicals, mitigating certain radical-generating pathways, maintaining the optimal ratio of reduced to oxidized glutathione, and protecting the endothelium against damage by toxic metabolites.66

GSH and other antioxidants can thus prevent oxidative stress, ameliorate vascular endothelial dysfunction, and stave off cardiovascular disease (among other chronic ailments).66


DHEA

The steroid hormone precursor dehydroepiandrosterone (DHEA) not only augments hormone production, but also positively affects eNOS. Supplementation with DHEA may thus further support endothelial health.67 A systematic review of 38 trials found that DHEA improves various aspects of sexual health in both males and females, including sexual interest, sexual frequency, lubrication, arousal, pain, and orgasm.68


Carnitine and Taurine

Carnitine and taurine have been shown to support NO production and vascular health. Specifically, propionyl-L-carnitine (PLC) has been observed to stimulate NO production and facilitate the delivery of free fatty acids into the mitochondria.69 When administered alongside acetyl-L-carnitine, PLC enhances the efficacy of sildenafil in treating the symptoms of ED in men who have undergone bilateral nerve-sparing prostatectomy.70

Taurine also increases NO, likely by decreasing asymmetric dimethylarginine (ADMA), as an inhibitor of NO synthesis.71,72

Meditation

Beyond erectile function and blood pressure, NO’s benefits include blood clot prevention, immune function enhancement, and nervous system support.7 NO may also contribute to the relaxing effects of meditation and mindfulness practice—and mindfulness practice may likewise enhance NO production.73 In one study, for example, experienced meditators were found to have lower levels of subjective stress and higher nitrate and nitrite levels.9 This finding may be added to the long list of reasons to recommend meditation and other mindfulness-based practices to those with ED and other cardiovascular ailments.


Exercise

Sedentary lifestyle is a significant risk factor for both ED and cardiovascular disease.9 Physical activity is known to increase vascular NO levels and improve vascular function,74 which explains at least in part why exercise is hailed as the lifestyle factor most strongly correlated with erectile health.74,75

A 2018 systematic review of 10 studies concludes that moderate to vigorous aerobic exercise four times weekly for six months improves erectile function in men who have ED caused by sedentary lifestyle, obesity, hypertension, cardiovascular disease, and/or metabolic syndrome.9 Considering that exercise helps with a wide array of other health conditions, physical activity should be a basic treatment guideline for just about every patient.


Conclusion

During sexual arousal, the vessels of the penis rely upon nitric oxide to help blood—and the oxygen and nutrients it carries—engorge the penis, resulting in tumescence. Erectile dysfunction may therefore represent poor endothelial health and a deficit of NO in many cases—and thus serve as a warning sign of more serious vascular ailments to come.

Because there is no standard lab test for assessing NO levels,76 it is important for healthcare providers to make astute clinical assessments of their patients’ cardiovascular status when labs and imaging fall short.

Simple, natural strategies and supplements—like oral health, digestive hygiene, green vegetables and beetroot, L-arginine, L-citrulline, glutathione, DHEA, carnitine, Pycnogenol, meditation, and exercise—may well serve the men who suffer from erectile dysfunction. Even in the context of testosterone replacement and phosphodiesterase inhibitor prescription, nitric oxide support may further improve sexual performance and safeguard against more serious vascular disease.

  • L-Arginine and L-Citrulline
  • Pycnogenol
  • Glutathione and Other Antioxidants
  • Carnitine and Taurine
  • __Berkeley Life Pro, __ M3 Powder, __  NO Max ER
  • Testosterone __ IM, __Troche,__ Topical
  • DHEA
  • Meditation
  • Exercise

Gut Health, Disease, Vit. D

Gut Health, Disease, Vit. D

Story at-a-glance

  • A significant proportion of your immune system resides in your gastrointestinal tract. Harvard researchers have now identified the specific population of gut bacteria that modulate localized and systemic immune responses to ward off viral invaders
  • Bacteroides fragilis and other bacteria in the Bacteroides family initiate a signaling cascade that induces the release of interferon-beta, which protects against viral invasion by stimulating immune cells to attack the virus and causing virus-infected cells to self-destruct
  • Zonulin-mediated gut permeability plays a determining role in the pathogenesis of many chronic inflammatory diseases. Zonulin is produced in response to bad bacteria. It flushes the bacteria out by opening up the tight junctions
  • Aside from bacteria overgrowth, gluten is a powerful trigger of zonulin release as the zonulin pathway misinterprets gluten as a potential harmful component of a microorganism
  • Chronic inflammatory diseases associated with dysregulation of the zonulin pathway and leaky gut include autoimmune disorders, metabolic disorders, intestinal diseases, neuroinflammatory diseases and cancer of the brain and liver

More attention than ever is being put on your gut health, and understandably so, considering a significant proportion of your immune system resides in your gastrointestinal tract.1 As such, optimizing your gut microbiome is a worthwhile pursuit that will have far-reaching effects on your physical health and emotional well-being.

Mounting scientific evidence also continues to suggest a large component of nutrition centers on nourishing health-promoting bacteria in your gut (and elsewhere in and on your body). In doing so, you keep harmful microbes in check and shore up your protection against chronic disease.

Disease Begins in Your Gut

ADHD, autism, learning disabilities, obesity, diabetes2 and Parkinson’s disease are but a few of the conditions found to be influenced by your gut microbiome. One 2020 scientific review3 goes so far as to say that all inflammatory disease begins in the gut. Part of the blame is laid on excessive hygiene. In other words, we’re “too clean” for our own good.

But your diet also plays a crucial role. The paper specifically addresses the role of zonulin-mediated gut permeability in the pathogenesis of chronic inflammatory diseases (CIDs). According to the author, Dr. Alessio Fasano,4 a pediatric gastroenterologist, researcher and director of the Center for Celiac Research and Treatment:5

“Apart from genetic makeup and exposure to environmental triggers, inappropriate increase in intestinal permeability (which may be influenced by the composition of the gut microbiota), a ‘hyper-belligerent’ immune system responsible for the tolerance-immune response balance, and the composition of gut microbiome and its epigenetic influence on the host genomic expression have been identified as three additional elements in causing CIDs.

During the past decade, a growing number of publications have focused on human genetics, the gut microbiome, and proteomics, suggesting that loss of mucosal barrier function, particularly in the gastrointestinal tract, may substantially affect antigen trafficking, ultimately influencing the close bidirectional interaction between gut microbiome and our immune system.

This cross-talk is highly influential in shaping the host gut immune system function and ultimately shifting genetic predisposition to clinical outcome. This observation led to a re-visitation of the possible causes of CIDs epidemics, suggesting a key pathogenic role of gut permeability.

Pre-clinical and clinical studies have shown that the zonulin family, a group of proteins modulating gut permeability, is implicated in a variety of CIDs, including autoimmune, infective, metabolic, and tumoral diseases. These data offer novel therapeutic targets for a variety of CIDs in which the zonulin pathway is implicated in their pathogenesis.”

Bacteria, Not Genes, Rule Your Health Destiny

Fasano points out that we simply do not have enough genes to account for the myriad chronic diseases that can beset us. Genes also cannot explain the timing of disease onset. To solve these mysteries, we must look to the microbiome, he says, as “it is the interplay between us as individuals and the environment in which we live that dictates our clinical destiny.”

Aside from the microbes themselves, the condition of your intestinal mucosa also plays a significant role. “Although this enormous mucosal interface (200 m2) is not apparently visible, it plays a pivotal role through its dynamic interactions with a variety of factors coming from our surrounding environment, including microorganisms, nutrients, pollutants and other materials,” Fasano explains.

While intracellular tight junctions used to be thought of as static and impermeable, we now know this is not the case. As explained by Fasano, zonulin is a powerful modulator of intestinal permeability. However, while zonulin is a biomarker of gut permeability and plays a pathogenic role in in many chronic inflammatory diseases, not all CIDs are caused by leaky gut.

Proposed Chain of Events Leading to CID

The graphic below, included in Fasano’s review but originating from an earlier paper6 titled “Zonulin, a Regulator of Epithelial and Endothelial Barrier Functions, and Its Involvement in Chronic Inflammatory Diseases,” co-written by Fasano and Craig Sturgeon, details the “proposed chain of events leading to chronic inflammatory disease.”

loss of mucosal immune homeostasis

Under normal circumstances, a healthy homeostasis is maintained in your gut lining such that when an antigen is encountered, no excess immune reaction occurs (anergy). Under No. 2 in the graph, gut dysbiosis is setting in (i.e., an imbalance in the number and diversity of your gut microflora), causing excess production of zonulin, which in turn makes the gut lining more permeable.

According to Fasano, the two most powerful triggers of zonulin release are bacteria overgrowth and gluten. Zonulin is produced in response to bad bacteria7 — it helps flush the bacteria out by opening up the tight junctions — so bacteria overgrowth makes sense. But why does it respond to gluten?

Interestingly enough, the zonulin pathway misinterprets gluten as a potential harmful component of a microorganism. That’s why gluten triggers zonulin release. While not mentioned by Fasano, the herbicide glyphosate also triggers zonulin, and is 10 times more potent than gluten!8

The subsequent permeability allows microbiota-derived antigen and endotoxin to migrate from the lumen to the lamina propria (the connective tissue that is part of the mucous membrane lining your intestine), thereby triggering inflammation.

As the process continues to worsen (No. 3 in the graph), your adaptive immune response kicks in, triggering the production of proinflammatory cytokines, including interferon gamma (IFN-γ) and tumor necrosis factor alpha (TNF-α). These cytokines further worsen the permeability, thus creating a vicious cycle. Eventually (No. 4), mucosal tolerance is completely broken, resulting in the onset of a chronic inflammatory disease.

Chronic Inflammatory Diseases Linked to Leaky Gut

The specific chronic inflammatory disease that ultimately emerges at the end of all this depends in part on your genetic makeup, in part on the types of exposures you’ve had, and in part on the composition of your gut microbiome. As explained by Fasano:9

“Besides genetic predisposition and exposure to environmental triggers, the pathogenesis of a variety of CIDs seems to involve mutually influenced changes in gut permeability/Ag trafficking, immune activation, and changes in composition/function of the gut microbiome.

Zonulin is a modulator of both epithelial and endothelial barrier functions … Gut dysbiosis may cause the release of zonulin leading to the passage of luminal contents across the epithelial barrier causing the release of pro-inflammatory cytokines that themselves cause increased permeability establishing a vicious loop leading to massive influx of dietary and microbial Ags triggering the activation of T cells.

Depending on the host genetic makeup, activated T cells may remain within the GI tract, causing CID of the gut … or migrate to several different organs to cause systemic CID.”

Chronic inflammatory diseases associated with dysregulation of the zonulin pathway include:

  • Autoimmune disorders such as Celiac disease, Type 1 diabetes, inflammatory bowel disease, multiple sclerosis and ankylosing spondylitis
  • Metabolic disorders such as obesity, insulin resistance, nonalcoholic fatty liver disease, gestational diabetes, hyperlipidemia and Type 2 diabetes
  • Intestinal diseases such as irritable bowel syndrome, non-celiac gluten sensitivity and environmental enteric dysfunction (a chronic disease affecting the proximal intestine)
  • Neuroinflammatory diseases such as autism spectrum disorder, schizophrenia, major depressive disorder and chronic fatigue/myalgic encephalomyelitis 
  • Brain and liver cancers

Gut Microbes Influence Genes and Can Influence Cancer Risk

While the inclusion of cancer on that list may seem odd at first glance, some researchers believe the gut microbiome may actually end up being a game-changer for cancer prevention and treatment.

Not only have gut bacteria been shown to influence gene expression,10,11 turning some genes on and others off, research12 published in 2018 found gut microbes actually control antitumor immune responses in your liver, and that antibiotics can alter the composition of immune cells in your liver, triggering tumor growth.

Harvard Medical School researchers have identified the specific population of gut microbes that modulates both localized and systemic immune response to ward off viral invaders.

Certain gut bacteria also promote inflammation, which is an underlying factor in virtually all cancers, whereas other bacteria quell it.13 The presence of certain gut bacteria has even been shown to boost the patient’s response to anticancer drugs.14

One way in which gut bacteria improve the effectiveness of cancer treatment is by activating your immune system and allowing it to function more efficiently. Researchers have actually found that when these specific microbes are absent, certain anticancer drugs may not work at all.

Gut Bacteria Are Part of Your Antiviral Defense

Gut bacteria are also involved in your antiviral defense, recent research15 shows. As reported by Harvard Medical School November 18, 2020:16

“For the first time, Harvard Medical School researchers have … identified the specific population of gut microbes that modulates both localized and systemic immune response to ward off viral invaders. The work … pinpoints a group of gut microbes, and a specific species within it, that causes immune cells to release virus-repelling chemicals known as type 1 interferons.

The researchers further identified the precise molecule — shared by many gut bacteria within that group — that unlocks the immune-protective cascade. That molecule, the researchers noted, is not difficult to isolate and could become the basis for drugs that boost antiviral immunity in humans.”

While the findings still need to be replicated and confirmed, they point to the possibility that you might be able to enhance your antiviral immunity by reseeding your gut with Bacteroides fragilis and other bacteria in the Bacteroides family.17

These bacteria initiate a signaling cascade that induces the release of interferon-beta that protect against viral invasion by stimulating immune cells to attack the virus and causing virus-infected cells to self-destruct.

“Specifically, … a molecule that resides on the bacterium’s surface triggers the release of interferon-beta by activating the so-called TLR4-TRIF signaling pathway,” Harvard explains.18 “This bacterial molecule stimulates an immune-signaling pathway initiated by one of the nine toll-like receptors (TLR) that are part of the innate immune system.”

The Role of Vitamin D

Recent research also highlights the role of vitamin D in gut health and systemic autoimmunity. The review article, published January 21, 2020, in Frontiers in Immunology, notes:19

“Autoimmune diseases tend to share a predisposition for vitamin D deficiency, which alters the microbiome and integrity of the gut epithelial barrier.

In this review, we summarize the influence of intestinal bacteria on the immune system, explore the microbial patterns that have emerged from studies on autoimmune diseases, and discuss how vitamin D deficiency may contribute to autoimmunity via its effects on the intestinal barrier function, microbiome composition, and/or direct effects on immune responses.”

As noted in this review, vitamin D has several direct and indirect regulatory effects on your immune system, including promoting regulatory T cells (Tregs), inhibiting differentiation of Th1 and Th17 cells, impairing development and function of B cells, reducing monocyte activation and stimulating antimicrobial peptides from immune cells.

That said, the relationship between vitamin D and autoimmunity is complicated. Aside from immunosuppression, vitamin D also appears to improve autoimmune disorders by the way it affects your microbiota composition and gut barrier.

The review cites research showing that your vitamin D status alters the composition of your gut microbiome. Generally speaking, vitamin D deficiency tends to increase Bacteriodetes and Proteobacteria while higher vitamin D intake tends to increase prevalence of Prevotella and reduce certain types of Proteobacteria and Firmicutes.

While research is still slim when it comes to vitamin D’s impact on gut bacteria, especially in patients with autoimmune disease, vitamin D deficiency and autoimmune diseases are known comorbidities and vitamin D supplementation is often recommended for these patients.

Vitamin D Required for Tight Junction Maintenance

Better known is how vitamin D supports intestinal and immune cell defenses in the gut. In fact, vitamin D is one of the crucial components required for maintaining tight junctions. As explained in this review:20

“The intestinal epithelium is in constant interaction with the external environment. Adequate barrier integrity and antimicrobial function at epithelial surfaces are critical in maintaining homeostasis and preventing invasion or overcolonization of particular microbial species.

A healthy intestinal epithelium and intact mucus layer are critical to protect against invasion by pathogenic organisms, and vitamin D helps to maintain this barrier function … Multiple studies found that vitamin D3/VDR signaling modulates tight junction protein quantity and distribution …

As a ‘leaky’ protein that allows movement of ions into the intestinal lumen, claudin-2 expression in the setting of functional vitamin D deficiency may contribute to colitis pathology …

Vitamin D upregulates antimicrobial peptide mRNA and protein expression including cathelicidin, defensins, and lysozyme … Antimicrobial peptides, primarily secreted by Paneth cells in the gut, are important mediators of microbiome composition … Defensins are secreted by epithelial cells, Paneth cells, and immune cells, and are important components of the innate immune response in the gut.”

How Vitamin D May Contribute to Autoimmune Disease

According to the authors, vitamin D deficiency may contribute to autoimmune disease by affecting the microbiome and the immune system in the following manner:

  1. Vitamin D deficiency or supplementation changes the microbiome, and manipulation of bacterial abundance or composition impacts disease manifestation.
  2. Lack of vitamin D signaling due to dietary deficiency can impair physical and functional barrier integrity of the gut, thereby allowing bacterial interactions to either stimulate or inhibit immune responses.
  3. Your innate immunologic defenses may be compromised if you are deficient in vitamin D.
vitamin D deficiency may contribute to autoimmune disease

How to Optimize Your Gut Microbiome

All of this information should really drive home the point that optimizing your gut flora and vitamin D level is of crucial importance for good health. By reseeding your gut with beneficial bacteria, you can keep pathogenic microbes and fungi in check and prevent them from taking over, and optimizing your vitamin D will help avoid leaky gut.

Regularly eating traditionally fermented and cultured foods is the easiest, most effective and least expensive way to make a significant impact on your gut microbiome. Healthy choices include lassi (an Indian yogurt drink), cultured grass fed organic milk products such as kefir and yogurt, natto (fermented soy) and fermented vegetables of all kinds.

Although I’m not a major proponent of taking many supplements (as I believe the majority of your nutrients need to come from food), probiotics are an exception if you don’t eat fermented foods on a regular basis. Spore-based probiotics, or sporebiotics, can be particularly helpful when you’re taking antibiotics. They’re also an excellent complement to regular probiotics.

Sporebiotics, which consist of the cell wall of bacillus spores, will help boost your immune tolerance, and because they do not contain any live bacillus strains, only its spores — the protective shell around the DNA and the working mechanism of that DNA — they are unaffected by antibiotics.

Antibiotics, as you may know, indiscriminately kill your gut bacteria, both good and bad. This is why secondary infections and lowered immune function are common side effects of taking antibiotics. Chronic low-dose exposure to antibiotics through your food also takes a toll on your gut microbiome, which can result in chronic ill health and increased risk of drug resistance. Last but not least, you also need to avoid things that disrupt or kill your microbiome, and this includes:

  • Antibiotics, unless absolutely necessary
  • Conventionally-raised meats and other animal products, as these animals are routinely fed low-dose antibiotics, plus genetically engineered and/or glyphosate-treated grains
  • Processed foods (as the excessive sugars feed pathogenic bacteria)
  • Chlorinated and/or fluoridated water
  • Antibacterial soap and products containing triclosan

The Push Catch Liver Detox

The Push Catch Liver Detox

A mainstay of my work has always been the Liver, Gallbladder & Ileo Cecal Valve. The main organs of detoxification. I decided to go back to my roots and reintroduce The PushCatch® LiverDetox- a versatile two-step cleansing protocol designed to help support the liver. It is widely accepted that eliminating toxins and then minimizing their redistribution and reabsorption is essential for proper health. Other improperly designed protocols on the market can result in unwanted redistribution, not elimination.*

This elegant and powerful formulation and delivery chemistry derive from Dr. Christopher Shade’s extensive research into detoxification pathways. In the “push” phase, powerful antioxidants assist a liposomal blend of bitters that support bile flow and help mobilize substances out of the tissues. Flowing into the gut, natural binders “catch” the compounds so that they can be safely eliminated by the body. Our PushCatch® contains a broad-spectrum constellation of binders that are blended with uniquely soothing prebiotic fibers.*

The PushCatch® Liver Detox integrates two unique Quicksilver Scientific products:

Dr. Shade’s Liver Sauce®: Certain botanicals have a potent effect on bitter receptors and phytonutrients can support healthy inflammatory response to support the different phases of liver detoxification and toxin elimination.* Dr. Shade’s Liver Sauce® contains a blend of four classic drainage botanicals and a synergistic medley of powerful phytonutrients.*

UltraBinder®: In the body, binders work across the gut to intercept and neutralize an array of toxins. UltraBinder™ contains a comprehensive, broad-spectrum binder, and because binders can be constipating, we added a soothing and fluidizing acacia gum and aloe vera to the blend.*

This system is highly flexible and can be used as a gentle, daily standalone detox, or as an intensive program.

Effective cleansing respects the fact that our body has built-in, highly evolved defense mechanisms that include adaptation, habituation, and a tendency to tilt toward homeostasis. Botanicals and phytonutrients that promote detoxification, drainage and elimination can be highly effective, but over time, the body may habituate to stimulation and become less responsive.

Cycling between on and off periods, and titrating doses from low to high over time are both key concepts essential for effective, safe detoxification. Cycling will give the body a necessary rest, and allow it to reset during the off period, so that detoxification can be resumed with full effect.

Titrating dosages and schedules up over time offers a scalable, flexible, and tolerated approach that is suitable for all, from the highly sensitive to the highly robust and resilient.

The PushCatch® LiverDetox can be adapted for very light frequent detoxification and can also be slowly scaled up for more intensive, deeper cleanses.

Suggested use:

1. Take a dose of Dr. Shade’s Liver Sauce, (remember to hold in mouth 30-60 seconds before swallowing.)

2. 30 minutes later take a dose of UltraBinder, then3. Wait 30 minutes before eating

Let’s do once a day before breakfast.  If that absolutely will not work then we will still do once a day between 1-4pm

Disclaimer: This system is not intended to diagnose or treat any disease. The dosing schedule below is designed to serve as a guide, and should not supplant guidance concerning the use of these supplements provided by your healthcare practitioner.

Caution: Because Ultra Binder™ contains activated charcoal and other substances which may affect the absorption of medications, it should be taken at least two hours before or after prescription medications.5 days on 2 days off!!    This is the Beginners program on the attached PDF


Dr. P’s Immune System Protocol

Immune System Supplements.JPG
Supplements to Strengthen /Support Immune System
Dr. P's Humdifier Technique .JPG
Dr. P’s Humidifier Technique
Immune System Supplements                                                                                                                                                                    Dr. P’s Humidifier Technique
   
Dr. David Brownstein Discusses Hydrogen Peroxide ++

This is really a great article because aside from Hydrogen Peroxide & Nebulizers, He mentions the importance of Iodine and other items that have always been on my protocol.

Most of you know my protocol for maintaining or creating a strong immune system. There are dozens of other products out there–my policy is to recommend the very best product at an affordable cost that I can guarantee will work. The protocols are as follows
Supplements
Beta 1,3 D Glucan  (1) daily
Astaxanthin  (1) daily
Vitamin D  (1) daily
Ormed Vitamin C  (5 drops (1x daily)
Detoxified Iodine Drops  (6 drops 1-2 daily)N Acetyl Cysteine NAC (1 cap or tab 1-2 x daily)  LUNGS
Techniques
Dr. P’s Humidifier Technique  (Physicians Strength Oregano, Peroxide, Silver 500, Distilled Water)
Nebulizer Hydrogen Peroxide (Food Grade Hydrogen Peroxide diluted down to 1-4% strength)
Nebulizer Mild Silver Protein 500 

**A reminder that 80% of our immune system is based in our Gut

TRUTH ABOUT WATERMELONS

The Truth about Watermelons…and Benefits

By: Catherine Ebeling 

Nothing says “Summer” better than a cool, refreshing, sweet, juicy, delicious slice of ripe watermelon—no matter what time of year it is. But I often hear cautions on eating watermelon—that it is high glycemic, full of sugar, mostly water, not very nutritious, etc.

NOTE: While watermelon does contain fruit sugar —fructose — like all other fruits, it is nearly 92 percent water. Just because it tastes sweet does not make it high in sugar. … This term, called glycemic load, is very low for watermelon — meaning that blood sugar is not changing much after eating it-but for diabetics, don’t overdo it!

Right? Or wrong?

While watermelons are mostly water—90% or so, they are also full of vitamins A, B6, C, lycopene, antioxidants and minerals. Remember hearing about the lycopene in tomatoes? Watermelon, another red-colored fruit, is FULL of this powerful phytonutrient! In fact, watermelon has some of the highest levels of lycopene of all fruits and veggies. Just one cup of watermelon has 1 and a half times the lycopene of a large fresh tomato. And who eats just one cup of watermelon? I know I don’t!

Because watermelon is one of the best sources of lycopene with more than 6,500 micrograms in less than half a cup, you are getting an army’s worth of inflammation-fighting antioxidant activity! Lycopene from the red flesh of watermelon is very stable, even after the watermelon has been cut and stored in the refrigerator. Lycopene is thought to be even more powerful than its other orange/red colored ally, beta carotene—found in red and orange fruits and veggies.

Cardiovascular Benefits

Lycopene is a powerful natural anti-inflammatory and antioxidant, valued for its role in protecting the cardiovascular system, bone health, and preventing cancer. Along with lycopene, watermelons contain another powerful phytochemical, citrulline, an amino acid. Citrulline gets converted into another important chemical in the body, arginine, or L-arginine. Arginine is used to create nitric oxide, which has powerful benefits on the heart and blood vessels. NO can actually cause blood vessels to relax and open up, lowering blood pressure and helping the body carry more oxygen to parts of the body where it is needed–like muscles, your heart and your brain. A study from Florida State University found that watermelon could make a significant difference in lowering blood pressure–especially in overweight people, by relaxing the blood vessel walls.

Citrulline, when it converts into arginine, can also help prevent excess accumulation of fat in fat cells, because it blocks an enzyme that stores this fat. And because citrulline is a precursor to nitric oxide, it can also help improve erectile dysfunction in men, in a similar way that Viagra works—although you would have to quite a bit of watermelon to get the same effect as Viagra.

As you can see in this article, watermelons are on the list of foods that beat statins for heart health!

It’s All About the Lycopene

Carotenoids are powerful antioxidants, capable of destroying free radicals which attack our bodies and can contribute to chronic disease and aging. In one study of 13,000 adult Americans, low levels of carotenoids were a key predictor of early death. Especially low blood levels of lycopene! Lycopene protects our cardiovascular system, the male reproductive system, and in the skin, it protects and prevents UV damage from the sun.

Several studies have been conducted showing the strong link between levels of lycopene and heart disease. Analyses from the Physicians Health Study showed a 39% decrease in stroke risk in men with the highest blood levels of lycopene. Another study in Finland following 1,000 men for 12 years has had similar results as well.

Lycopene is also responsible for limiting the enzyme responsible for making cholesterol, so eating foods with more lycopene also helps to reduce cholesterol—specifically, LDL cholesterol.

Anti-Cancer Power

Lycopene is a life-saver in more ways than one! Besides its cardiovascular benefits, lycopene’s antioxidant power extends to anti-cancer effects as well. A 2014 meta-analysis of 10 studies shows dietary lycopene to be protective against ovarian cancers, as well as brain tumors and breast tumors.

And of course, we know about lycopene’s value in fighting prostate cancer. In several studies, higher intakes of foods containing lycopene and a higher serum or plasma concentration of lycopene was associated with a very significant decreased risk of prostate cancer—especially the more lethal kind of prostate cancer. When researchers studied only the men who had had at least one high risk PSA test, the subjects had a 50% decreased risk of lethal prostate cancer.

“Based on these results, we hypothesize that the consumption of a diet rich in lycopene-containing foods reduces the aggressive potential of prostate cancer by inhibiting the neoangiogenesis that occurs in tumor development,” Dr. Giovannucci’s team reported online ahead of print in the Journal of the National Cancer Institute.”

Other studies have shown lycopene’s powerful cancer fighting ability effective against lung cancer, esophageal, stomach, pancreatic, colorectal, and cervical cancers as well.

Extremely Good for Rehydration

Watermelons get their name because they are over 90% water, and that water is full of electrolytes and potassium which helps you stay hydrated or to rehydrate. The perfect fruit to eat on hot summer days, or after a hard, sweaty workout! And that delicious juice can also help prevent muscle soreness—especially if you have watermelon before your intense workout.

It’s Not Just the Red Part

While most of us only eat the juicy red flesh of the watermelon, the whole thing is actually edible and chock full of nutrients! From the red center to the stem end, and also the blossom end–including the white part near the rind–are a plethora of impressive antioxidants, flavonoids, lycopene, and vitamin C. Even the green rind is full of nutrients. The rind is full of chlorophyll, and contains even more citrulline than the red flesh. Try throwing your watermelon rinds into the blender with fresh squeezed lime juice for a healthy slushy treat.

It is still best, however, to pick ripest, reddest watermelon you can find. Lycopene content continues to increase all the way up until the time the watermelon is at its reddest and ripest.

And don’t spit out those seeds, unless you are in a watermelon seed-spitting contest! The black watermelon seeds are not only edible, but actually extremely good for you. They are full of iron, zinc, fiber and protein. Seedless watermelons are ok to eat too—they are not genetically modified, only hybrid forms of watermelon bred especially for their no-seed content.

Watermelons also are rich in anti-inflammatory substances including cucurbitacin E, triterpenoid which help to block the pain and inflammation of certain enzymes, in a similar fashion as NSAID’s like ibuprofen and aspirin.

While being very low in calories (only about 46 calories in a cup), watermelon also contains an impressive variety of other important essential nutrients including:

  • Vitamin A
  • Vitamin C
  • Vitamin B6
  • Potassium
  • Magnesium

The Age-Old Question—How Do You Pick the Perfect Watermelon?

It can be a huge gamble finding the perfect, red, sweet watermelon. But—if you know what to look for, there is a real method to finding the best one. Look on the underside of the watermelon for a pale, butter-colored yellow spot—not white or green. This is one of the best indicators of the ripeness of the watermelon. Also pick up a few and choose the one that is heaviest for its size. Many people ‘thump’ the watermelon to check its ripeness too—listen for the best hollow bass sound.

Be aware that watermelons do contain a reasonable quantity of fructose, so be mindful of your sugar intake, and eat watermelon in moderation.  With that said, because watermelons are so filling, and have both high water content AND high fiber content, the old myth that watermelons are high glycemic is not entirely true… This is because the “glycemic load” of a watermelon is actually fairly low since it’s nearly impossible to overeat large quantities of a food that is as filling as watermelon