Acid Reflux – The Diet and Beyond

Acid Reflux – The Diet and Beyond

Reflux occurs when the lower esophageal sphincter (LES, between the esophagus and the upper portion of the stomach) becomes overly loose, allowing stomach contents to move upward, back into the esophagus. The problem, therefore, is not excess hydrochloric acid, but rather, a weakened LES. There are certain foods that may weaken the LES, such as chocolate, peppermint and alcohol. Food timing and post-meal activities are also factors. Individuals with an already weakened LES are advised not to consume large meals shortly before bed, since lying down can increase the pressure on the LES and cause reflux. Reclining in general after a meal may have the same result. It might not be comfortable for people to watch TV while sitting upright after dinner, but this position may give gravity a leg up in warding off reflux.Another factor that may exacerbate acid reflux is obesity—specifically, abdominal obesity, where fat is mainly carried at the midsection. A larger concentration of body mass in the abdominal area means increased pressure on the LES, with greater reflux being an obvious potential consequence. Certainly, not all overweight individuals experience reflux, and plenty of lean individuals do. So excess body weight is not an ironclad cause of reflux; it’s simply one among many contributors that could be addressed if an overweight patient experiences frequent heartburn.

There are, of course, foods that exacerbate acid reflux. But it’s important to note that they do just that—exacerbate, but not cause—the issue. At the top of the list are acidic foods, such as citrus fruits, tomatoes and coffee. Alliums—which include garlic, onions and shallots—may also be a factor. The acidity and irritating potential of these foods do not cause reflux. When the LES is already weakened, these foods may be particularly irritating to the esophagus, which, unlike the stomach, is not coated in a layer of protective mucus.

Elimination diets have had some efficacy in relieving heartburn and indigestion. Individuals who adopt Paleo or “Primal”-style diets often experience complete relief, suggesting that refined grains, damaged oils and processed foods may contain LES-offending elements. Patients who experience acid reflux may benefit from keeping a food log, which could help them identify foods that trigger episodes of heartburn, specifically, and indigestion, more broadly.

An additional factor that may result in acid reflux is hiatal hernia. Again, it is unlikely that a hernia is the initial cause of reflux, but it may be a potentiating force upon an already weakened LES. Large hernias may impair timely esophageal emptying, resulting in prolonged acid exposure after an incidence of reflux. This would be especially true in the supine position, again hinting at the importance of remaining upright for some time after a meal.

When food sensitivities, psychological stress, body weight, alcohol intake, cigarette smoking and anatomical issues have been addressed and/or ruled out, and an individual still suffers from unpleasant acid reflux, an additional factor to explore is delayed gastric emptying. As mentioned earlier, this is often due to insufficient, rather than excessive, stomach acid. With inadequate HCl, food—in particular, protein—is not broken down sufficiently to trigger the opening of the pyloric sphincter, which would allow food to move from the stomach into the duodenum. As food remains in the stomach for an extended amount of time, the proteins may putrefy and carbohydrates may ferment, resulting in increased pressure upon the LES. The remedy for this would not be acid blocking drugs, but rather, increased acidity in the stomach, delivered in the form of HCl supplements, or perhaps lemon juice or vinegar taken with meals.

Due to its multiple causes, acid reflux can be difficult to treat. It’s not as simple as quitting coffee and avoiding spicy takeout food. Some cases may require a multi-pronged strategy to keep symptoms at bay, including targeted supplementation, lifestyle modifications and the identification of triggering foods.

Note:  I spent a career on this issue.  Just know Antacids are not the answer because the issue is NOT TOO MUCH ACID, but TOO Little.  My post on HCL Deficiency and Proton Pump Inhibitors will provide a plethora of information and answers.

Call or write me and we will figure it out!

Proton Pump Inhibitors

 Proton Pump Inhibitors Worse than the Indigestion they Supposedly Cure

A class of antacid medications known as proton pump inhibitors (PPIs) has now been proven to be quite harmful. Some common PPIs include Nexium, Prilosec, Prevacid, and Protonix. Many of these are available over the counter with no prescription. Proton pump inhibitors are used in the management of simple heartburn, gastro-esophageal reflux and peptic ulcer disease. PPIs decrease acid in the stomach by blocking an enzyme that is needed for the production of hydrochloric acid.

The FDA itself has issued a warnings about these drugs, including statements that they cause low magnesium and increased risk of osteoporosis. PPIs increase the risk of infectious diarrhea caused by such organisms as Clostridium difficile (C. diff). This infection often requires hospitalization, treatment with various IV antibiotics, and can be fatal in the very young, elderly and immuno-compromised individuals. PPIs also inhibit the absorption of vitamin B12 and calcium, and have multiple drug interactions. Higher doses and long-term use of PPIs greatly increase the risks.

Fracture Risk: The FDA has come out with a warning to health care professionals and consumers that PPIs lead to increased risk of fractures of the hip, wrist and spine. This warning is based on the agency’s own review of several studies.

A study published in the Journal of the American Medical Association found that patients over age 50 who were treated with PPIs for over a year had a 44% increased risk of hip fracture. High doses and long tern use increased this risk even more. At the same time PPIs inhibit the absorption of calcium, they inhibit the proton pumps in the cells which build new bone. This leads to osteoporosis due to both calcium deficiency and impaired ability to build new bone.

Low magnesium: In 2011, the FDA issued a warning that PPIs can induce low magnesium if taken for long periods of time. They recommended that prescribers obtain a serum magnesium test prior to initiation of therapy and periodically thereafter. In patients taking Digoxin for heart conditions, low magnesium greatly increases its toxicity. In 25% of patients who developed low magnesium, supplements were not enough to correct this, and the drug had to be discontinued.

Magnesium is a critical mineral and is needed for virtually every function of the body. It activates enzymes, is involved in energy production, regulates heartbeat and muscle contractions, and regulates calcium, copper, zinc, potassium, Vitamin D and many other nutrients present in the body.

Deficiency of magnesium can cause heart arrhythmias, profound weakness and fatigue, restless leg syndrome, confusion, jerky muscle movements, and high blood pressure.

Be aware that the bottom of the “normal” range for serum magnesium is so low that it is not going to pick up a problem until the person is already very ill. It is nearly impossible to take too much magnesium unless there is a problem with the kidneys. If serum magnesium levels get too high, the kidneys will excrete it. Also, oral magnesium, especially magnesium oxide, at higher doses will cause diarrhea and can be excreted this way.

Drug Interactions: These are listed in the material given with the OTC products, but how many people read and comprehend these tiny inserts?

Plavix (anti-coagulant): The FDA issued a warning to avoid taking PPIs and Plavix together as concurrent use can decrease the effectiveness of Plavix by up to 50%. This in turn could lead to blood clots, stroke and heart attacks.

Warfarin(Coumadin, anti-coagulant): PPIs inhibit breakdown of this drug in the liver, leading to high blood levels which can cause hemorrhage.

Diazepam (Valium, tranquilizer): Due to less breakdown in the liver caused by PPIs, high blood levels can result in respiratory depression, respiratory arrest, extreme fatigue, sleepiness, and confusion.

Antiretrovial agents (drugs used to treat HIV/AIDS): PPIs increase blood levels of these drugs, leading to increased side effects.

Tacrolimus (used to prevent rejection of transplanted organs): PPIs increase blood levels of this drug which cause significant problems.

Antifungals: These drugs are dependent on low pH in the stomach for absorption. Therefore, when acid production is inhibited, they are not absorbed and are thus ineffective. Any drug dependent on normal stomach acidity for absorption will be affected similarly

Treat heartburn and reflux naturally

If you have persistent heartburn and/or reflux, there are non-drug solutions. First determine the cause of the problem. Reflux is caused by a weak lower esophageal sphincter (LES). This is the doughnut shaped muscle that allows food to enter the stomach. The more common cause of heartburn/reflux is weakening of the LES caused by low stomach acid.

The hydrochloric acid produced by the stomach functions to break down proteins into amino acids, stimulates the pancreas and small intestine to secrete digestive enzymes, and prevents infection by killing pathogenic bacteria and yeasts commonly present in foods. Correcting low acid in the stomach will virtually stop heartburn/reflux without drugs. There are a few things you can do at home to help determine if your problem is low stomach acid.

  1. The baking soda test: Mix 1/4 teaspoon of baking soda in 8 ounces of water and drink it. Do this first thing in the morning before eating or drinking anything. Start timing and note how long before you belch. If you have adequate stomach acid, you should belch within 2 or 3 minutes. Stop timing at 5 minutes. No belching within 5 minutes is a good indicator of low stomach acid. Early and excessive belching may indicate excessive stomach acid.
  1. Trial of Betaine HCL: Using a product such as Gastro Plus, take 1 to 2 capsules immediately prior to eating. You may feel a sensation of warmth, but not burning. If you feel burning, discontinue use as your problem may be excess stomach acid, which is very rare. Under the guidance of a qualified professional, the dose may be titrated upwards until you feel burning, then decreased to the point where you don’t feel any actually burning. A healthy stomach produces many times the amount of hydrochloric acid found in this product.

There are medical tests which actually measure the amount of acid produced by the stomach, and some lab tests can indicate low stomach acidity. Stool analysis will show elevated short chain fatty acids. Blood tests will indicate amino acid, B vitamins and mineral deficiencies.

Some dietary and lifestyle changes can also help alleviate symptoms:

  • Eliminate sugar and refined carbohydrates
  • Keep a food diary and eliminate foods which cause or worsen the problem Many of the foods conventional medicine warns you to avoid may be fine, so listen to your own body
  • Keep the head of your bed elevated at least 6 inches until symptoms are resolved. This helps prevent the reflux of acid back into the esophagus through the LES
  • Quit smoking
  • Don’t wear tight clothing, such as belts, bras or tight waistband
  • Remain upright for an hour or more after eating
  • Avoid eating close to bedtime

For more information:

https://drprincetta.com/hcl-hydrochloric-acid-deficiency/

http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm213377.htm

http://www.raysahelian.com/protonpumpinhibitor.html

http://jama.ama-assn.org/content/296/24/2947.abstract

http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm245275.htm

http://www.drdebe.com/stomach-acid-assessment.html