What is Methylation?
B-Vitamins such as Folic Acid & B12 act as methyl donors and change gene expression for the positive even in utero.
When a methyl group attaches to a specific spot on a gene –a process called DNA Methylation–it can change the genes expression turning it off or on, dampening or making it louder.
GSH an Methylation block the process of cell suicide triggered by stresses that the cell cannot overcome– such as an increase of the presence of free radicals (toxins) or a loss in the cells ability to produce energy (ATP)
Functions of Methylation:
- Epigenetics (Turns Genes On/Off)
- Protects and Stabilizes DNA
- Stress Adaptation (Activates + Deactivates Stress Hormones
- Effects Mood (Activates Serotonin, Melatonin and Dopamine)
- Energy (ATP) Production
- Detoxification
- Growth + Healing
- Autonomic Nervous System (ANS)
- Immune System (activates and deactivates histamine)
- Involved in every aspects of the disease process
Methyl Depletion Symptoms:
- Chronic Fatigue
- S;eep Disorders
- Inability to Adapt to Stress
- Toxic Encephalitis
- Genetic Disorders
- Hormone Dysregulation
- Cancer
- Weight Loss Resistance (cannot lose weight with improper methylation)
What causes Depletion of Methyl Groups:
- Genetics
- Diet
- a) Over consumption of Sugar increase histamine production
- b) A deficiency of B12=Folate (not eating enough quality meat (B12) and Vegetables (Folate)
- Malabsorption (Decreases B12 + Folate)
- Toxins
- Stress Hormone Dysregulation and HRT
Methylation’s Effect on Hormones:
- Phase II Estrogen Metabolism is dependent on methylation for the removal of toxic estrogen metabolites
- An increase in toxicity or stress can deplete the body of methyl groups and cause a build up of toxic estrogen
- This phenomenon has become EPIDEMIC in both sexes leading to cancer and a host of other unwanted symptoms
Methylation’s Effect on The Nervous System
- Increases Pain Sensitivity
- Temperature Dysregulation
- Increase + Decrease in Blood Pressure
- Organ Dysmobility
- Pulse Irregularities
- Cognitive Decline (Brain Fog)
- Immune Deficiency
- Disruption of Cortisol Melatonin Circadian Coordination Rhythm (Sleep + Anxiety)
- Hyper/Hypoglycemia (Energy + Sleep)
NOTE: The body cannot differentiate as to the type or cause of the stress. All it know is that it is stress and as such has to defer it to protect itself!